Severe Anemia Is Associated with Intestinal Injury in Preterm Neonates

Ozcan B., AYDEMİR Ö., Isik D. U., BAŞ A. Y., DEMİREL N.

AMERICAN JOURNAL OF PERINATOLOGY, vol.37, no.6, pp.603-606, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.1055/s-0039-1683982
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.603-606
  • Keywords: anemia in the preterm neonate, fatty acid binding proteins, intestinal injury, necrotizing enterocolitis, red blood cell transfusion, BLOOD-CELL TRANSFUSIONS, ACID-BINDING PROTEIN, NECROTIZING ENTEROCOLITIS
  • Eskisehir Osmangazi University Affiliated: Yes


Objective A temporal relationship has been reported between necrotizing enterocolitis, anemia, and red blood cell transfusion (RBCT) in preterm neonates. However, the mechanism underlying this association is not clearly defined. Intestinal (I-) and liver (L-) fatty acid binding proteins (FABPs) have been proposed as plasma markers for the detection of acute intestinal injury. This study aimed to investigate the effect of anemia and RBCT on intestinal injury in preterm neonates by measuring serum I-FABP and L-FABP levels.