Mutagenicity of 1- Ethyl- 2,4,5- triphenyl- 1H- imidazole and Six Derivatives in Salmonella typhimurium

Mercangoz A., KORKMAZ F.

GAZI UNIVERSITY JOURNAL OF SCIENCE, cilt.25, sa.1, ss.1-8, 2012 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 1
  • Basım Tarihi: 2012
  • Dergi Adı: GAZI UNIVERSITY JOURNAL OF SCIENCE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.1-8
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Newly synthesized 1-Ethyl-2,4,5-triphenyl-1H-imidazole and its six derivatives were tested by Ames assay. In order to reveal the mutagenic activities of the compounds, two different mutant strains of Salmonella typhimurium (TA98 and TA100) were used in an Ames assay with/without S9 microsomal fraction from rat liver. It was found that the compounds have no mutagenic activities.