Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.38, sa.4, ss.285-292, 2010 (Scopus)
Aim: The present study aims to compare the effects of anesthesia induction in children with sevoflurane and propofol on QT and corrected QT (QTc) interval durations. Material and Method: A total of 40 paediatric patients were included in this prospective study. Control electrocardiograms (ECG) were recorded before induction. In the sevoflurane group (Group S), anaesthesia was induced by sevoflurane. In the propofol group (Group P), induction was performed using propofol. In all patients, ECGs were obtained at the first and third minutes of induction, 3 minutes after administration of muscle relaxant and 5 minutes after initiation of intubation. QT durations were measured directly from ECG records, while QTc intervals were estimated using Bazett formula. Results: There was no significant difference in QT and QTc duration of control ECG records in groups S and P. In Group S, QTc estimates obtained 3 minutes after induction, 3 minutes after administration of the muscle relaxant and 5 minutes after the intubation were significantly longer than those of Group P (p<0.05). Conclusion: In our study, we found that QTc durations were significantly prolonged in the paediatric patients that received anaesthesia induction with sevoflurane rather than propofol. We conclude that propofol could be first preference for the induction of paediatric patients with a predisposition to preoperative arrhythmia and those with prolonged QTc durations.