The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury

Karabeyoglu, Melih; Unal, BÜLENT; Bozkurt, Betuel; Dolapci, Istar; Bilgihan, Ayse; Karabeyoglu, Isil; Cengiz, Oemer

doi:10.1016/j.jss.2007.02.050

The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury

Karabeyoglu M., Unal B., Bozkurt B., Dolapci I., Bilgihan A., Karabeyoglu I., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.144, sa.1, ss.59-63, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 144 Sayı: 1
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.jss.2007.02.050
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.59-63
Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Background. Thermal injury causes a breakdown in the intestinal mucosal barrier due to ischemia reperfusion injury, which can induce bacterial translocation (BT), sepsis, and multiple organ failure in burn patients. The aim of this study was to investigate the effect of ethyl pyruvate (EP) on intestinal oxidant damage and BT in burn injury.