Akademik Veri Yönetim Sistemi
Uluslararası Klinik Araştırmalar Dergisi, cilt.1, sa.2, ss.41-45, 2016 (Hakemli Dergi)
Butyrylcholinesterase (BCHE) deficiency, several drugs or administration of high doses of succinylcholine (SCh) are well known reasons for prolonged succinylcholine clearance. The goal of this study was to investigate the relationship between hemoglobine (Hb) levels and SCh metabolism for the parturients undergoing cesarean sections. One hundred and twenty patients were randomized into three groups (n=40). In Group 1, the Hb levels of the patients were between 9-11 g dL–1. In Group 2, the levels were between 11 g dL–1 and 13 g dL–1. Finally in Group 3, the Hb levels of the patients were between 13-15 g dL–1. The BChE levels, Hb levels, the time for recovery of neuromuscular function were compared between groups. Group demographics were similar. There was no significant difference between Groups 1 and 2 regarding their drug elimination time (p>0.05). The recovery of neuromuscular functions was significantly faster in Group 3 (p<0.05). The results of our study suggest that anemia may cause prolonged SCh-induced paralysis and apnea for the patients undergoing cesarean section. Key words: Succinylcholine, cesarean, hemoglobine, butyrylcholinesterase.