7th INTERNATIONAL “ACHARAKA” CONGRESS ON MEDICINE, NURSING, MIDFIWERY, AND HEALTH SCIENCES, Ürgenç, Özbekistan, 20 - 22 Haziran 2024, cilt.01, sa.1, ss.370-373, (Özet Bildiri)
Objectives Sudden cardiac death (SCD) is a major international public health problem, responsible for an estimated 15–20% of all deaths. According to autopsy findings, SCD can be triggered by exercise due to ischemic heart disease, cardiac hypertrophy and myocardial scarring. However, considering the general population, regular physical activity contributes to a significant reduction in the risk of cardiovascular mortality, depending on the activity level. The aim of this study is to examine the effect of different durations of physical activity on the risk of SCD in women.
Methods A computerized literature search was conducted from the earliest available date to April 2024 using the PubMed and Web of Science databases using the following MeSH terms; (((death) AND (sudden)) AND (((exercise) OR (physical activity)) OR (sports activity))) AND ((((hour) OR (hours)) OR (hourly)) OR (minute)). Among the 1100 articles scanned, 2 prospective studies reporting adjusted relative risk (RR) estimates and 95% confidence intervals (CI) of weekly physical activity duration and sudden cardiac death in women were included. A random effects model was used to estimate summary RRs (95% CIs) because different populations were evaluated in the studies.
Results The reduction in SCD risk was found to be significant in women who did physical activity for 4 hours or more per week (RR, 0.55; 95% CI, 0.39-0.78; P=0.001; I2: 36.1%) compared with women who did less than 1.9 hours (RR, 0.82; 95% CI, 0.63-1.07; P=0.150; I2: 0%) and between 2- 3.9 hours (RR, 1.01; 95% CI, 0.67-1.53; P=0.939; I2: 50.6%) per week. Conclusion: According to the results of this meta-analysis, exercising 4 hours or more per week significantly reduces the risk of SCD in women. Further studies are needed to evaluate the optimal duration and intensity of physical activity to reduce the risk of SCD in women. Keywords: Physical activity, Sudden cardiac death, Meta-analysis.