Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents

Erguc A., ALTINTOP M. D., ATLI Ö., SEVER B., İŞCAN G., Gormus G., ...Daha Fazla

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.15, sa.2, ss.193-202, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1570180814666171003145227
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.193-202
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Background: In medicinal chemistry, thiazoles have gained great importance in anti-fungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone derivatives and evaluate their anticandidal and anticancer effects.