Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents

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Erguc A., ALTINTOP M. D., ATLI Ö., SEVER B., İŞCAN G., Gormus G., ...More

LETTERS IN DRUG DESIGN & DISCOVERY, vol.15, no.2, pp.193-202, 2018 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 15 Issue: 2
• Publication Date: 2018
• Doi Number: 10.2174/1570180814666171003145227
• Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.193-202
• Eskisehir Osmangazi University Affiliated: No

Abstract

Background: In medicinal chemistry, thiazoles have gained great importance in anti-fungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone derivatives and evaluate their anticandidal and anticancer effects.