Jinekoloji ve Obstetri Bulteni, vol.6, no.2, pp.51-57, 1997 (Scopus)
Objective: To evaluate the correlation between the uterine artery doppler blood flow velocity indexes and the serum human chorionic gonadotrophine (hCG) levels in gestational trophoblastic disease (GTD). Study design: Ten cases with histopathological diagnosis of GTD were evaluated totally 20 times by serum hCG level and uterine artery doppler blood flow velocity measurements with an interval of at least one week. The relations between the indexes obtained from the same artery, between the indexes of the right and the left uterine arteries and between the serum hCG levels and the mean indexes calculated for that evaluation, were evaluated by paired test and correlation analysis. Results: Significant correlations were obtained between the indexes obtained from the same uterine artery and between the indexes of the right and left uterine arteries (p<0.0001). Insignificant negative correlations were observed between the absolute values of serum hCG levels and mean doppler systole/diastole ratios, resistance indexes and pulsatility indexes of every case (p>0.05), however, significant negative correlations were found between the logarithmic values of the serum hCG levels and the same doppler indexes, with correlation coefficients of -0.63, -0.48 and -0.50, respectively (p<0.05). Conclusion: It was thought that, index values of both the right or the left uterine artery could reflect the vascular alterations of uterus occurred in GTD and uterine artery doppler indexes, which were significantly correlated with serum hCG level, could be used during the follow-up of this disease.