Copy For Citation
Gungor E. M., SEVER B., ALTINTOP M. D., AKALIN ÇİFTÇİ G.
LETTERS IN DRUG DESIGN & DISCOVERY, vol.17, no.11, pp.1380-1392, 2020 (SCI-Expanded)
-
Publication Type:
Article / Article
-
Volume:
17
Issue:
11
-
Publication Date:
2020
-
Doi Number:
10.2174/1570180817999200618163507
-
Journal Name:
LETTERS IN DRUG DESIGN & DISCOVERY
-
Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE
-
Page Numbers:
pp.1380-1392
-
Eskisehir Osmangazi University Affiliated:
No
Abstract
Background: Akt is overexpressed or activated in a variety of human cancers, including gliomas, lung, breast, ovarian, gastric and pancreatic carcinomas. Akt inhibition leads to the induction of apoptosis and inhibition of tumor growth and therefore extensive efforts have been devoted to the discovery of potent antitumor drugs targeting Akt.