Synthesis of some dithiocarbamate derivatives and their antimicrobial activity

Kaplancikli Z., Turan-Zitouni G., Revial G., Iscan G.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol.179, no.7, pp.1449-1454, 2004 (SCI-Expanded) identifier identifier


Some new, 2-[(N-substituted aminothiocarbonylthio)acetyl]aminothiazole, N-substituted aminothiocarbonylthioacetylaminodiphenylmethane and 9-[(N-substituted aminothiocarbonylthio)acetyl]aminofluorene derivatives were synthesized by reacting 2-(chloroacetyl) aminothiazole, chloroacetylaminodiphenylmethane, and 9-(chloroacetyl)aminothiazole, with secondary amine dithiocarbamate derivatives in acetone respectively. The structure elucidation of the compounds was performed by IR, H-1-NMR, and FAB(+)-MS spectral data. The substances were tested for their antimicrobial activity.