Growth hormone and the risk of atherosclerosis in growth hormone-deficient children

Binay C., ŞİMŞEK E., Yildirim A., Kosger P., Demiral M., Kilic Z.

GROWTH HORMONE & IGF RESEARCH, cilt.25, sa.6, ss.294-297, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.ghir.2015.08.005
  • Dergi Adı: GROWTH HORMONE & IGF RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.294-297
  • Anahtar Kelimeler: Growth hormone deficiency, Carotid intima-media thickness, Atherosclerosis, INTIMA-MEDIA THICKNESS, GH REPLACEMENT THERAPY, LEFT-VENTRICULAR MASS, BONE-MINERAL DENSITY, CARDIOVASCULAR RISK, CARDIAC-PERFORMANCE, CAROTID ARTERIES, BODY-COMPOSITION, ADULT PATIENTS, LIPOPROTEIN LEVELS
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Growth hormone-deficient (GHD) children have been found to have higher cardiovascular mortality rates and an increased carotid intima-media thickness (CIMT). This study investigated the risk of atherosclerosis and the effect of recombinant growth hormone (rhGH) replacement therapy on the lipid profile and CIMT in GHD children.