Growth hormone and the risk of atherosclerosis in growth hormone-deficient children

Binay C., ŞİMŞEK E., Yildirim A., Kosger P., Demiral M., Kilic Z.

GROWTH HORMONE & IGF RESEARCH, vol.25, no.6, pp.294-297, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1016/j.ghir.2015.08.005
  • Journal Name: GROWTH HORMONE & IGF RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.294-297
  • Keywords: Growth hormone deficiency, Carotid intima-media thickness, Atherosclerosis, INTIMA-MEDIA THICKNESS, GH REPLACEMENT THERAPY, LEFT-VENTRICULAR MASS, BONE-MINERAL DENSITY, CARDIOVASCULAR RISK, CARDIAC-PERFORMANCE, CAROTID ARTERIES, BODY-COMPOSITION, ADULT PATIENTS, LIPOPROTEIN LEVELS
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: Growth hormone-deficient (GHD) children have been found to have higher cardiovascular mortality rates and an increased carotid intima-media thickness (CIMT). This study investigated the risk of atherosclerosis and the effect of recombinant growth hormone (rhGH) replacement therapy on the lipid profile and CIMT in GHD children.