Akademik Veri Yönetim Sistemi
Anestezi Dergisi, cilt.15, sa.2, ss.134-139, 2007 (Scopus)
Objective: We aimed to compare the effects of bolus remifentanil, alfentanil and esmolol on cardiovascular responses to laryngoscopy and tracheal intubation. Method: ASA I-II physical status: sixty patients aged 18-65 and scheduled for elective surgery were included in the study. Patients were randomly divided into three groups. Group A received 20 μg kg1 alfentanil, Group E received 2 mg kg-1 esmolol, and Group R received 2 μg kg1 remifentanil one minute after induction. Hemodynamic values were noted before (control) and after induction of anesthesia, one minute after the study drug, and 1, 3, 5 and 10 minutes after intubation. Results: SAP values significantly increased in Group E compared with Groups A and R at 1, 3 and 5 min after intubation (p<0.001), whereas there was no significant difference between alfentanil and remifentanil (p>0.05). There were no significant differences in heart rate between the groups (p>0.05). SAP values were significantly changed in Group R and Group E compared with the baseline one min after intubation (p<0.001) whereas there was no significant change in Group A (p>0.05). Heart rate increased significantly in Group A compared with the baseline after intubation (p<0.01), whereas there was no statistically difference in Group R and Group E (p>0.05). Conclusion: We found that with laboring doses of remifentanil and alfentanil in our study are more effective than esmolol in preventing hemodynamic responses to direct laringoscopy and intubation.