Familial Mediterranean fever: An updated review

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Sari I., Birlik M., KAŞİFOĞLU T.

EUROPEAN JOURNAL OF RHEUMATOLOGY, cilt.1, sa.1, ss.21-33, 2014 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 1 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/eurjrheum.2014.006
  • Dergi Adı: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.21-33
  • Anahtar Kelimeler: Familial Mediterranean fever, review, aetiology, amyloidosis, treatment, PROTRACTED FEBRILE MYALGIA, GENOTYPE-PHENOTYPE CORRELATION, NERVOUS-SYSTEM INVOLVEMENT, ACUTE-PHASE RESPONSE, SUBCLINICAL INFLAMMATION, COLCHICINE TREATMENT, RISK-FACTOR, AUTOINFLAMMATORY SYNDROMES, CLINICAL-PATTERNS, IMAGING FINDINGS
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterised by acute attacks of fever and serosal inflammation. FMF primarily affects Jewish, Armenian, Turkish, and Arab populations. The disease is accompanied by a marked decrease in quality of life due to the effects of attacks and subclinical inflammation in the attack-free periods. Untreated or inadequately treated patients run the risk of amyloidosis, which is an important cause of morbidity and mortality. In this review, the current information available on FMF is summarised.