Familial Mediterranean fever: An updated review

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Sari I., Birlik M., KAŞİFOĞLU T.

EUROPEAN JOURNAL OF RHEUMATOLOGY, vol.1, no.1, pp.21-33, 2014 (ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 1 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.5152/eurjrheum.2014.006
  • Journal Name: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.21-33
  • Keywords: Familial Mediterranean fever, review, aetiology, amyloidosis, treatment, PROTRACTED FEBRILE MYALGIA, GENOTYPE-PHENOTYPE CORRELATION, NERVOUS-SYSTEM INVOLVEMENT, ACUTE-PHASE RESPONSE, SUBCLINICAL INFLAMMATION, COLCHICINE TREATMENT, RISK-FACTOR, AUTOINFLAMMATORY SYNDROMES, CLINICAL-PATTERNS, IMAGING FINDINGS
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterised by acute attacks of fever and serosal inflammation. FMF primarily affects Jewish, Armenian, Turkish, and Arab populations. The disease is accompanied by a marked decrease in quality of life due to the effects of attacks and subclinical inflammation in the attack-free periods. Untreated or inadequately treated patients run the risk of amyloidosis, which is an important cause of morbidity and mortality. In this review, the current information available on FMF is summarised.