Serological and Molecular Investigation of the Presence and Association of Toxoplasma gondii in Bipolar Affective Disorder and Schizophrenic Patients

DOĞAN N., Akdas I., Essizoglu A., GÜLEÇ G.

FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, cilt.23, sa.3, ss.142-149, 2018 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5578/flora.67297
  • Dergi Adı: FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.142-149
  • Anahtar Kelimeler: Toxoplasma gondii, Bipolar affective disorder, Schizophrenia, INFECTIOUS AGENTS, ANTIBODIES, RISK, ETIOPATHOGENESIS, INDIVIDUALS
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Introduction: Toxoplasma gondii is an intracellular parasite that affects about one third of the population in developed countries. It is known that in the brain and muscle tissues of infected people, this parasite maintains its stagnant phase lifelong. T. gondii relation, in terms of neurotropism is shown up to 60% in anxiety, depression, even schizophrenic psychoses. Schizophrenia and bipolar affective disorder (BAD) are neuropsychiatric disorders seen worldwide and their etiologies are not fully understood. Recently, it is suggested that although it is clinically indefinite, it may be a neurotropic agent, such as the trophozoites of the parasite, that have a special affinity to the glia cells of the brain.