Akademik Veri Yönetim Sistemi
POLYMER BULLETIN, cilt.76, sa.7, ss.3709-3731, 2019 (SCI-Expanded)
Although much focus has been placed in the recent years to find new nanofiber-based materials produced by electrospinning medicinal plant extracts, there is no study to determine plant extract-polymer compatibility and matching in terms of antibacterial activity and nanofiber morphology. In this study, we aim to produce nanomats with effective antimicrobial properties by combining the polymers used in the medical field with the extracts obtained from various plants in Turkey via electrospinning technique. In line with this goal, three medicinal natural herbal extracts of Hypericum perforatum (HP), Agrimonia eupatoria (AE) and Satureja hortensis (SH) were used after an intensive analyzing of nine medicinal plants as antibacterial and healing agents from the country flora. Several composite nanofibers have been obtained by electrospinning technique, and the best polymer-extract compatibility with demonstrating 18 and 22mm inhibition zone against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), respectively, was observed for thermoplastic polyurethane (TPU)/SH composite. Later on, detailed studies of TPU/SH nanofiber were continued. Taken together, antibacterial and morphological properties of the composite nanofibers can be controlled by selecting the polymer and extract types properly for various wound care dressings. Antimicrobial, air permeability, morphological and chemical properties of the obtained composite nanofibers were also analyzed and evaluated.