Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia

Dernek S., Ikizler M., Erkasap N., Ergun B., Koken T., Yilmaz K., ...More

SCANDINAVIAN CARDIOVASCULAR JOURNAL, vol.38, no.4, pp.245-254, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1080/14017430410035476
  • Journal Name: SCANDINAVIAN CARDIOVASCULAR JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.245-254
  • Keywords: antioxidant, ischemia, pretreatment, reperfusion, resveratrol, RED WINE, VASORELAXING ACTIVITY, REPERFUSION INJURY, OXIDATIVE STRESS, FREE-RADICALS, CONSUMPTION, INHIBITION, QUERCETIN, MORTALITY, KINETICS
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective-The major objective of the present study is to evaluate the potential role of resveratrol (RVT), a natural antioxidant found in grapes and red wine, in protecting the myocardium from the deleterious effects of ischemia-reperfusion (I/R) injury using isolated rat hearts.