Water-Clear Cell Adenoma of the Mediastinal Parathyroid Gland

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ARIK D., DÜNDAR E., YILMAZ E., Sivrikoz C.

TURKISH JOURNAL OF PATHOLOGY, cilt.35, sa.2, ss.157-161, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5146/tjpath.2017.01407
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.157-161
  • Anahtar Kelimeler: Water-clear cell, Adenoma, Ectopic tissue, Mediastinum, Parathyroid gland, PRIMARY HYPERPARATHYROIDISM, ULTRASTRUCTURE, HYPERPLASIA, PATHOLOGY, PATIENT
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Water-clear cell adenoma of the parathyroid gland is a rare neoplasm that consists of cells with abundant clear-pink cytoplasm. There have only been 19 cases reported in the English literature. Here we report a case of water-clear cell adenoma of the mediastinal parathyroid gland. A 70-year-old male patient presented to the hospital with back pain and a mediastinal mass 6 cm in size was detected. After excision and microscopic evaluation, uniform, large clear cells with fine cytoplasmic vacuolization, without nuclear atypia, and arranged in solid and acinar patterns were revealed. The cells formed nests that were separated by fine fibrovascular septae and stained positively with anti-parathyroid hormone. To the best of our knowledge, this has not been previously reported in this location. In the differential diagnosis of clear cell lesions of the mediastinum, water-clear cell parathyroid adenoma should be considered.