Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study


Brouwer W. P., Chan H. L. Y., Lampertico P., Hou J., Tangkijvanich P., Reesink H. W., ...More

CLINICAL INFECTIOUS DISEASES, vol.69, no.11, pp.1969-1979, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 69 Issue: 11
  • Publication Date: 2019
  • Doi Number: 10.1093/cid/ciz084
  • Journal Name: CLINICAL INFECTIOUS DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1969-1979
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background. (Pegylated) Interferon ([Peg]IFN) therapy leads to response in a minority of chronic hepatitis B (CHB) patients. Host genetic determinants of response are therefore in demand.