Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study

Brouwer, Willem; Chan, Henry; Lampertico, Pietro; Hou, Jinlin; Tangkijvanich, Pisit; Reesink, Hendrik; Zhang, Wenhong; Mangia, Alessandra; Tanwandee, Tawesak; Montalto, Giuseppe; Simon, Kris; Ormeci, Necati; Chen, Liang; Tabak, Fehmi; Gunsar, Fulya; Flisiak, Robert; Ferenci, Peter; Akdogan, Meral; Akyuz, Filiz; Hirankarn, Nattiya; Jansen, Louis; Wong, Vincent; Soffredini, Roberta; Liang, Xieer; Chen, Shalom; Groothuismink, Zwier; Santoro, Rosanna; Jaroszewicz, Jerzy; Ozaras, Resat; Kozbial, Karin; Brahmania, Mayur; Xie, Qing; Chotiyaputta, Watcharasak; Xun, Qi; Pazgan-Simon, Monika; Oztas, ERKİN; Verhey, Elke; Montanari, Noe; Sun, Jian; Hansen, Bettina; Boonstra, Andre; Janssen, Harry; Brouwer, Willem; Hansen, Bettina; Verhey, Elke; Boonstra, Andre; Janssen, Harry; Chi, Heng; Sonneveld, Milan; Montanari, Noe; de Knegt, Rob; Chan, Henry; Wong, Vincent; Wong, Grace; Lampertico, Pietro; Borghi, Marta; Loglio, Alessandro; Soffredini, Roberta; Hou, Jinlin; Sun, Jian; Liang, Xieer; Tangkijvanich, Pisit; Hirankarn, Nattiya; Sodsai, Pimpayao; Chuaypen, Natthaya; Reesink, Henk; Jansen, Louis; Zhang, Wenhong; Chen, Shalom; della Sofferenza, Casa; Mangia, Alessandra; Santoro, Rosanna; Tanwandee, Tawesak; Chotiyaputta, Watcharasak; Montalto, Guiseppe; Simon, Kris; Pazgan-Simon, Monika; Ormeci, Necati; Chen, Liang; Qun, Xi; Tabak, Fehmi; Ozaras, Resat; Gunsar, Fulya; Flisiak, Robert; Jaroszewicz, Jerzy; Ferenci, Peter; Kozbial, Karin; Akdogan, Meral; Oztas, Erkin; Akyuz, Filiz; Janssen, Harry; Brahmania, Mayur; Feld, Jordan; Noureldin, Seham; Guo, Simin; Xie, Qing

doi:10.1093/cid/ciz084

Genome-wide Association Study Identifies Genetic Variants Associated With Early and Sustained Response to (Pegylated) Interferon in Chronic Hepatitis B Patients: The GIANT-B Study

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Brouwer W. P., Chan H. L. Y., Lampertico P., Hou J., Tangkijvanich P., Reesink H. W., ...More

CLINICAL INFECTIOUS DISEASES, vol.69, no.11, pp.1969-1979, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 69 Issue: 11
Publication Date: 2019
Doi Number: 10.1093/cid/ciz084
Journal Name: CLINICAL INFECTIOUS DISEASES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1969-1979
Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background. (Pegylated) Interferon ([Peg]IFN) therapy leads to response in a minority of chronic hepatitis B (CHB) patients. Host genetic determinants of response are therefore in demand.