Akademik Veri Yönetim Sistemi
The 39th Annual Meeting of the European Society of Paediatric Infectious Diseases (ESPID), Geneve, İsviçre, 24 - 29 Mayıs 2021, cilt.1, sa.512, ss.836
Background: Syphilis is a bacterial infection caused by Treponema pallidum that results in substantial morbidity and mortality. Congenital syphilis is usually devastating to the fetus if the maternal infection is not detected and treated sufficiently early in pregnancy. The burden of morbidity and mortality due to congenital syphilis is high.
Case Presentation Summary: A forty-two days old girl brought with fever, exfoliating fingertips, and circular erythematous lesions on extremities and body surface. It’s learned that her mother was drug-addicted. Laboratory examination showed hemoglobin 7.8 g/dL, leukocyte 16.400/mm3 , C-reactive protein 60.2 mg/L, Treponema pallidum total antibody 27.47 (0,99-1), Treponema pallidum blotting test positive. With this clinical situation, congenital syphilis was thought of as a diagnosis. Before the antimicrobial treatment, lumbar puncture for cranial involvement and Treponema pallidum blotting test for the cerebrospinal fluid sample was positive but protein and glucose level couldn’t be evaluated because of the traumatic procedure. Penicillin G 50.000 unit/dose three times a day was given to the patient for ten days. In clinical observation, the patient's exanthems were gone, the fever did not see after treatment. Eye examination, hearing test, and cranial ultrasonography were planned. Six months after treatment, it was planned to take lumbar puncture again for central nervous system involvement.
Learning Points/Discussion: Typical signs and symptoms may occur in infants with congenital syphilis
or they may be completely asymptomatic at birth. In the first few months of life, clinical results may
become noticeable; however, the infection may remain undetected in some of these children until the
symptoms of late congenital syphilis are apparent.