Acute renal failure and lactic acidosis seconder to metformin intoxication Metformin intoksikasyonuna sekonder gelişen akut böbrek hasarı ve laktik asidoz

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AYDAR H., TEZCAN N., MUTLUAY R.

Pamukkale Medical Journal, vol.15, no.2, pp.379-382, 2022 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.31362/patd.900939
  • Journal Name: Pamukkale Medical Journal
  • Journal Indexes: Scopus, Central & Eastern European Academic Source (CEEAS), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.379-382
  • Keywords: acute renal failure, lactic acidosis, Metformin intoxication
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Metformin is a oral antidiabetic drug being class of biguanid. It reduces hepatic glucose production by inhibiting gluconeogenesis, improves peripheral insulin sensivity. The well known serious side effects are acute renal failure and lactic asidosis. Metformin is the most commonly prescribed drug because of its cost-effectiveness and existing in first line theraphy in guidelines for type 2 diabetes mellitus. We report a case a patient with known hypertension and new diagnosis diabetes mellitus, presenting acute renal failure and lactic acidosis seconder to taking overdose metformin in suicide attempt.