Acute renal failure and lactic acidosis seconder to metformin intoxication Metformin intoksikasyonuna sekonder gelişen akut böbrek hasarı ve laktik asidoz

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Aydar H., Tezcan N., Mutluay R.

Pamukkale Medical Journal, cilt.15, sa.2, ss.379-382, 2022 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.31362/patd.900939
  • Dergi Adı: Pamukkale Medical Journal
  • Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.379-382
  • Anahtar Kelimeler: acute renal failure, lactic acidosis, Metformin intoxication
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Metformin is a oral antidiabetic drug being class of biguanid. It reduces hepatic glucose production by inhibiting gluconeogenesis, improves peripheral insulin sensivity. The well known serious side effects are acute renal failure and lactic asidosis. Metformin is the most commonly prescribed drug because of its cost-effectiveness and existing in first line theraphy in guidelines for type 2 diabetes mellitus. We report a case a patient with known hypertension and new diagnosis diabetes mellitus, presenting acute renal failure and lactic acidosis seconder to taking overdose metformin in suicide attempt.