Akademik Veri Yönetim Sistemi
Polish Journal of Radiology, cilt.89, ss.140-147, 2024 (ESCI)
Purpose: Solid pancreatic lesions might have overlapping findings in portal venous phase computed tomography (CT). In this study, we aimed to investigate the quantitative and qualitative imaging features of solid pancreas lesions based on subtype and grade. Material and methods: The study group consisted of 159 patients with solid pancreatic tumours detected after exclu-sion criteria. According to the pathology results, the patients were divided into 3 groups as PDAC (pancreatic ductal adenocarcinoma, n = 137), PNET (pancreatic neuroendocrine tumour, n = 15), and SC (sarcomatoid carcinoma, n = 7). PDAC and PNET lesions were evaluated in 3 subgroups according to grade. Results: There was no difference between the groups in terms of age, gender, tumour localisation, and internal struc-ture (p = 0.23, p = 0.81, p = 0.19, and p = 0.94, respectively). Qualitative features significantly differed in terms of tumour margin feature, visual tumour density, presence of cystic component, and presence of necrosis (p = 0.01, p = 0.0001, p = 0.002, and p = 0.004, respectively). Tumour size, Tmden,Tm/VP, and Tm/PanP showed dif-ferences between groups (p = 0.0001, p = 0.002, p = 0.0001, p = 0.0001, respectively). The presence of cystic density den den den den in PDAC patients differed according to grade (p = 0.01). Conclusions: While ill-defined irregular margins, hypodense visual tumour density, no cystic component, low value of Tmden, andlow ratios of Tm/VP and Tm/PanP indicate PDAC, regular margins, iso-or hyperdense visual den den den den tumour density, cystic component, high value of Tmden, and high ratios of Tmden/VPden and Tmden/PanPden indicate PNET. SC can be differentiated from them by containing necrosis and reaching larger sizes. The presence of a cystic component in PDAC patients indicates high grade.