Intermittent Subcutaneous Injections of Apomorphine in Parkinson's Disease

CEYLAN M., GÜLTEKİN M., Celik N. D., SAMANCI B., YALÇIN ÇAKMAKLI G., YILMAZ R.

EURASIAN JOURNAL OF MEDICINE, cilt.54, 2022 (ESCI) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 54
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/eurasianjmed.2022.22134
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

The intermittent subcutaneous injection of apomorphine is highly effective in the management of motor and non-motor symptoms of Parkinson's disease. Although it has been shown that apomorphine injection can be safely used in selected cases at all stages of the disease, there is no consensus regarding intermittent administration strategies. This review aimed to discuss the indications for intermittent subcutaneous apomorphine use in clinical practice, possible side effects and their management, and contraindicated cases in light of the literature and to present practical recommendations for clinical practice.