Devices like computers that require manual control are difficult to use by disabled people such as having multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), partial stroke, etc. These people have a very limited movement capability such that they can do most of the interaction with a limited movement of head and the eye. Assistive technologies are very important for people with disabilities not to be dependent on anyone in daily life. In this study, we present a human -computer interaction application that works based on analysis of the head and eye/eyebrow movements from real-time images captured by a visual camera. We propose Difference Between Eye and Eyebrow (DEEB) features to detect the action intention of the user and properly realize the computer keyboard and mouse actions based on eyebrow, eye and head movements. In addition, there are shortcut keys in the designed interface that facilitate access to Instagram, WhatsApp, YouTube etc. which are considered to make it easier for individuals with disabilities to communicate with their social environment. We obtained satisfactory results on the designed interface in the experimental study.