Butrylcholinesterase Activity in Chronic Liver Disease Patients and Correlation with Child-Pugh Classification and MELD Scoring System

TEMEL H. E., TEMEL T., ÜSKÜDAR CANSU D., ÖZAKYOL A.

CLINICAL LABORATORY, vol.61, pp.421-426, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61
  • Publication Date: 2015
  • Doi Number: 10.7754/clin.lab.2014.141111
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.421-426
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: After 40 years since establishment of Child-Pugh staging, 14 years since establishment of MELD scoring system, and 25 years since establishment of King's College Criteria, there is still a search for more accurate systems for determination of prognosis in patients with acute liver failure - cirrhosis and prioritization for receipt of a liver transplant - prediction of post transplant mortality. Butrylcholinesterase is an enzyme which is synthesized in the liver. The aim of the study was to evaluate the clinical utility of butrylcholinesterase as a discriminatory and prognostic factor in chronic liver disease patients.