Dietary polyphenol quercetin protects rat hearts during reperfusion: enhanced antioxidant capacity with chronic treatment

Ikizler M., Erkasap N., DERNEK S., Kural T., Kaygisiz Z.

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.7, no.4, pp.404-410, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 4
  • Publication Date: 2007
  • Journal Name: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.404-410
  • Keywords: quercetin, heart, ischemia/reperfusion, protection, oxidative stress, antioxidant, ISCHEMIA-REPERFUSION, FREE-RADICALS, INJURY, SUPEROXIDE, RESVERATROL, MECHANISM, RELEASE, SERUM
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: Quercetin is an important member of dietary flavonoid family and widely present in red wine and Mediterranean diet. The major objective of the this study is to evaluate the beneficial effects of quercetin in protecting the myocardium from the deleterious effects of ischemia reperfusion (I/R) injury in chronic quercetin treatment with or without an acute quercetin infusion protocols.