An Evaluation of the Autofluorescence Changes with Wide-Angle Digital Fundus Camera in Chronic Central Serous Chorioretinopathy Patients

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Bilgeç M. D., Yaşar E., Erol N.

Osmangazi Tıp Dergisi, vol.44, no.6, pp.755-760, 2022 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2022
  • Doi Number: 10.20515/otd.1092900
  • Journal Name: Osmangazi Tıp Dergisi
  • Journal Indexes: TR DİZİN (ULAKBİM)
  • Page Numbers: pp.755-760
  • Eskisehir Osmangazi University Affiliated: Yes


To evaluate the autofluorescence variations and localisation in wide-angle digital fundus camera images of patients with chronic central serous chorioretinopathy (CSCR). A retrospective scan was made of the images of patients diagnosed with chronic CSCR with wide-angle digital fundus angiography and applied at the same time with autofluorescence imaging. The ultra wide area autofluorescence images of 46 patients were examined. The retina was separated as zone 1, zone 2, and zone 3 in respect of disease involvement, and zone 3 represented the peripheral retina. The images of the patients were recorded as hyperautofluorescence (punctate, diffuse) or hypo-autofluorescence (granular, confluent) in respect of the type of autofluorescence involvement. After the exclusion of 2 patients because peripheral images could not be clearly selected, the study evaluations were made of 44 eyes of 44 patients. The mean duration of the disease was found to be 2.7 years. In the result of the examination with wide-angle digital fundus autofluorescence imaging, there was seen to be zone 2 involvement in the 4 quadrants of inferior, nasal, temporal and superior. Peripheral retinal involvement in zone 3 was seen in a total of 7 (15.9%) patients in the form of inferior gravitational defect, in 6 (13.6%) patients together with zones 1 and 2, and in 1 (2.3%) patient together with zone 2. Hyperautofluorescence was determined in 39 (88.6%) patients and hypo-autofluorescence in 5 (11.4%). The involvement frequency was determined as zone 1+2 in 19 (43.2%) patients, followed by zone 1 involvement alone in 16 (36.4%) patients. Common autofluorescence type was detected as hyperautofluorescence in chronic CSCR patients with a high rate of approximately 90%. It has also been shown that in some patients, the disease may also affect the inferior peripheral retina due to the effect of gravity. Keywords: central serous chorioretinopathy, wide-angle digital fundus autofluorescence, peripheral retina, hyperautofluorescence, hypo-autofluorescence