Genetic variants associated with atrial fibrillationand long-term recurrence after catheter ablation for atrialfibrillation in Turkish patients.


Ulus T. , Dural M. , Meşe P., Yetmiş F., Mert K. U. , Görenek B. , ...More

Anatolian journal of cardiology, vol.25, no.2, pp.129-138, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.14744/anatoljcardiol.2020.44082
  • Title of Journal : Anatolian journal of cardiology
  • Page Numbers: pp.129-138
  • Keywords: atrial fibrillation, single nucleotide polymorphisms, catheter ablation, CHROMOSOME 4Q25 VARIANTS, 2016 ESC GUIDELINES, RISK-FACTOR, SUSCEPTIBILITY

Abstract

Objective: Genome-wide association studies have revealed that single nucleotide polymorphisms (SNPs) are associated with atrial fibrillation (AF) and can predict AF recurrence after catheter ablation in different populations. However, there exists no such data for the Turkish population. We aimed to investigate whether 11 SNPs in the PITX2, ZFHX3, EPHX2, CAV1, TBX5, TGF-1, and SCN10A were related to AF and whether these SNPs can predict long-term atrial tachyarrhythmia (ATa) recurrence after pulmonary vein isolation (PVI) for AF in Turkish patients.