Genetic variants associated with atrial fibrillationand long-term recurrence after catheter ablation for atrialfibrillation in Turkish patients.

Ulus T., Dural M., Meşe P., Yetmiş F., Mert K. U., Görenek B., ...Daha Fazla

Anatolian journal of cardiology, cilt.25, sa.2, ss.129-138, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.14744/anatoljcardiol.2020.44082
  • Dergi Adı: Anatolian journal of cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.129-138
  • Anahtar Kelimeler: atrial fibrillation, single nucleotide polymorphisms, catheter ablation, CHROMOSOME 4Q25 VARIANTS, 2016 ESC GUIDELINES, RISK-FACTOR, SUSCEPTIBILITY
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Genome-wide association studies have revealed that single nucleotide polymorphisms (SNPs) are associated with atrial fibrillation (AF) and can predict AF recurrence after catheter ablation in different populations. However, there exists no such data for the Turkish population. We aimed to investigate whether 11 SNPs in the PITX2, ZFHX3, EPHX2, CAV1, TBX5, TGF-1, and SCN10A were related to AF and whether these SNPs can predict long-term atrial tachyarrhythmia (ATa) recurrence after pulmonary vein isolation (PVI) for AF in Turkish patients.