Synthesis, Antibacterial, Antifungal, Antimycobacterial Activity Evaluation of Novel 1,2,4-triazole Derivatives Bearing 4-Aminophenyl Moiety


Cavusoglu B. K., YURTTAŞ L., CANKILIÇ M. Y., KAPLANCIKLI Z. A.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.14, sa.8, ss.938-948, 2017 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 8
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1570180814666161130103624
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.938-948
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Background: In this work, 2-[[5-(4-aminophenyl)-4-(4-substituted phenyl)-4H-1,2,4-triazol- 3-yl] thio]-1-(4-substituted phenyl) ethan-1-one derivatives (1-15) and 2-[[5-(4-aminophenyl)-4-( 4-substituted phenyl)-4H-1,2,4-triazol-3-yl] thio]-N-(4-substituted phenyl) acetamide derivatives (15-30) were synthesized using 4-aminobenzohydrazide as starting material.