Surveillance and control of meningococcal disease in the COVID-19 era: A Global Meningococcal Initiative review.

Alderson M. R., Arkwright P. D., Bai X., Black S., Borrow R., Caugant D. A., ...Daha Fazla

The Journal of infection, cilt.84, sa.3, ss.289-296, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 84 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.jinf.2021.11.016
  • Dergi Adı: The Journal of infection
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Aquatic Science & Fisheries Abstracts (ASFA), CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.289-296
  • Anahtar Kelimeler: COVID-19, Coronavirus, Pandemic, Vaccination, Neisseria meningitidis, Invasive meningococcal disease, Serogroup, Antibiotic resistance, Sexual transmission, RESISTANT NEISSERIA-MENINGITIDIS, CIPROFLOXACIN-RESISTANT, REDUCED SUSCEPTIBILITY, EMERGENCE, URETHRITIS, VACCINE, PREVENTION, COLUMBUS, AFRICA, OHIO
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

This review article incorporates information from the 4th Global Meningococcal Initiative summit meeting. Since the introduction of stringent COVID-19 infection control and lockdown measures globally in 2020, there has been an impact on IMD prevalence, surveillance, and vaccination compliance. Incidence rates and associated mortality fell across various regions during 2020. A reduction in vaccine uptake during 2020 remains a concern globally. In addition, several Neisseria meningitidis clonal complexes, particularly CC4821 and CC11, continue to exhibit resistance to antibiotics, with resistance to ciprofloxacin or beta-lactams mainly linked to modifications of gyrA or penA alleles, respectively. Beta-lactamase acquisition was also reported through horizontal gene transfer (bla ROB-1) involving other bacterial species. Despite the challenges over the past year, progress has also been made on meningococcal vaccine development, with several pentavalent (serogroups ABCWY and ACWYX) vaccines currently being studied in late-stage clinical trial programmes. Crown Copyright (C) 2021 Published by Elsevier Ltd on behalf of The British Infection Association.