ANNALS OF PLASTIC SURGERY, vol.81, no.6, pp.715-724, 2018 (SCI-Expanded)
Article / Article
ANNALS OF PLASTIC SURGERY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
angiogenesis, apoptosis, burn, mesenchymal stem cell, oxidative stress, stasis zone, PARTIAL THICKNESS BURNS, OXIDATIVE STRESS, FREE-RADICALS, INJURY, APOPTOSIS, DEATH, SKIN, ZONE, REGENERATION, NECROSIS
Eskisehir Osmangazi University Affiliated:
Introduction Burns are dynamic wounds that may present a progressive expansion of necrosis into the initially viable zone of stasis. Therefore, salvage of this zone is a major subject of focus in burn research. The beneficial effects of mesenchymal stem cells (MSCs) on the survival of the zone of stasis have been previously documented. However, many gaps still exist in our knowledge regarding the underlying protective mechanisms. Hence, this study was designed to evaluate the pathophysiological basis of MSCs in the prevention of burn wound progression.