CAN SYSTEMIC IMMUNE INFLAMMATORY INDEX PREDICT HOSPITALIZATION NEED IN COVID-19?


Alagöz R., Yaman N. E., Acar N., Çanakçı M. E.

8th Eurasian Congress of Emergency Medicine & 18th Emergency Medicine Congress of Turkey & 17th World Interactive Network Focused on Critical Ultrasound Congress, Antalya, Türkiye, 1 - 04 Aralık 2022, ss.274-275

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Antalya
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.274-275
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

OBJECTIVE: The exaggerated and uncontrolled inflammatory response is one of the main reasons for COVID-19 disease

severity. The systemic immune-inflammatory index (SII) is a parameter that reflects the immune and inflammatory status of

the organism. It has also started to be used in the early evaluation of critically ill patients.Our study aimed to determine the

relationship between SII levels and hospitalization and mortality status in patients with a positive COVID-19 PCR test.

MATERIAL and METHODS: Patients who presented to Eskişehir Osmangazi University Emergency Department between

August 1, 2020, and October 31, 2020, and were found to have positive PCR tests were evaluated retrospectively.

Demographic data, vital parameters, comorbidities, and hospital outcomes of the patients were compared.

RESULT:A total of 402 patients were included in the study and 50.7% were women. The median age was 69 [54-79] years. The

most common complaints were shortness of breath (34.3%), cough (28.4%), and fatigue (17.9%). 208 patients were

hospitalized (51.7%), 136 patients (33.8%) were discharged from ED, 50 patients were admitted to the intensive care unit

(12.4%), and 8 patients died in the ED (2.0%). 56 patients died after hospitalization.

Since 8 patients were exitus in ED, according to the evaluations made out of 394 patients. The hospitalized patients were

older, and had lower saturation, higher leukocyte counts, lower lymphocyte counts, and higher SII values (respectively

p<0.001, p<0.001, p=0.028, p<0.001, p<0.001). Comparisons made according to the need for hospitalization are given in Table

1. In the evaluation made in terms of mortality, the SII value was found to be high, but no statistical difference was found

(Table 2).

CONCLUSION: Although there are many retrospective studies in the literature on COVID-19, there is still no clear consensus

on prognostic factors affecting the disease. Since the number of patients who died after hospitalization was low in our study,

significant differences in SII values may not have been observed. However, in terms of showing the need for hospitalization,

the SII index is a parameter that can be used both for COVID-19 and for other infectious and inflammatory conditions.