Ivabradine treatment prevents dobutamine-induced increase in heart rate in patients with acute decompensated heart failure

ÇAVUŞOĞLU Y., Mert U., Nadir A., MUTLU F., Morrad B., ULUS T.

JOURNAL OF CARDIOVASCULAR MEDICINE, cilt.16, sa.9, ss.603-609, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.2459/jcm.0000000000000033
  • Dergi Adı: JOURNAL OF CARDIOVASCULAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.603-609
  • Anahtar Kelimeler: acute heart failure, dobutamine, ivabradine, CORONARY-ARTERY-DISEASE, RATE REDUCTION, CONTROLLED-TRIAL, BETA-BLOCKERS, FUNNY CURRENT, RISK-FACTOR, OUTCOMES, MORTALITY, DEATH
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background Ivabradine is a heart rate (HR)-lowering agent acting by inhibiting the I-f-channel. Dobutamine does increase the HR and has some deleterious effects on myocardium. So, we aimed to evaluate whether ivabradine treatment blunts a dobutamine-induced increase in HR.