Akademik Veri Yönetim Sistemi
European Society of Endodontology 22nd biennial congress “Challenges, Opportunities and New perspectives in Endodontology” , Paris, Fransa, 3 - 06 Eylül 2025, sa.175, (Özet Bildiri)
AIM: An effective irrigation process is crucial for the long-term success of endodontic treatment and currently
no single solution meets all the requirements of root canal treatment. As a result, different endodontic
solutions are often used sequentially or novel solution combinations and devices are being evaluated to
achieve faster and more effective endodontic treatment. The objective of this investigation was to conduct
analytical comparisons of two novel solution combinations -Endoxal and QMix2in1- with established
analytical standards.
Methodology: Endoxal and Qmix2in1 and analytical-grade corresponding materials; ethylene diamine
tetraacetic acid (EDTA) and chlorhexidine (CHX) were studied for the chromatographic and spectroscopic
experiments. Fourier transform infrared (FTIR) spectroscopy and ultra-high-performance liquid
chromatography (UHPLC) were performed. Cloudy-white precipitate was seen in the experimental mixture of
CHX and EDTA; however, the clear liquid form was noted in both Endoxal and QMix2in1. UHPLC revealed
that the CHX content in the Endoxal and QMix solutions was 313.26 ppm and 31.11 ppm, respectively.
Endoxal and QMix functional groups mostly overlapped in FTIR spectral assignments, but the experimental
mixture did not.
Results: • CHX concentration in Endoxal is approximately tenfold greater than Qmix2in1.
• A greater concentration of surfactant may have been practical to inhibit interaction with EDTA, given
the comparatively high concentration of CHX in Endoxal.
• The concerns regarding the toxicity of surfactants, particularly CTAB, demand more inquiry into the
toxicity levels of these mixed irrigation solutions.