Biotransformation of alpha-Cedrol and Caryophyllene Oxide by the Fungus Neurospora crassa
NATURAL PRODUCT COMMUNICATIONS, cilt.5, sa.4, ss.515-518, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 5 Sayı: 4
- Basım Tarihi: 2010
- Doi Numarası: 10.1177/1934578x1000500403
- Dergi Adı: NATURAL PRODUCT COMMUNICATIONS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.515-518
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Incubation of a-cedrol and caryophyllene oxide with Neurospora crassa afforded 12 beta-hydroxy cedrol, 10 alpha-hydroxy cedrol, and 3 beta-hydroxy cedrol, and 12 beta-hydroxy caryophyllene oxide as major metabolites, respectively. The antibacterial and radical scavenging activities of the metabolites were evaluated in vitro using broth microdilution and bioauthographic techniques. However, no significant antibacterial and antioxidant activities were observed when compared with those of standard substances.