The clinical and economic burden of varicella in the Middle East: a systematic literature review

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Al Kaabi N., Al Olama F. M. A. S., Al Qaseer M., Al Ubaidani I., DİNLEYİCİ E. Ç., Hayajneh W. A., ...Daha Fazla

HUMAN VACCINES & IMMUNOTHERAPEUTICS, cilt.16, sa.1, ss.21-32, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/21645515.2019.1638726
  • Dergi Adı: HUMAN VACCINES & IMMUNOTHERAPEUTICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.21-32
  • Anahtar Kelimeler: Middle East, seroprevalence, systematic literature review, varicella, vaccination, HEALTH-CARE WORKERS, VACCINE-PREVENTABLE DISEASES, ZOSTER-VIRUS, SAUDI-ARABIA, HEPATITIS-A, SEROPREVALENCE, CHILDREN, COMPLICATIONS, CHICKENPOX, RUBELLA
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

This systematic literature review was conducted to better understand the epidemiology and burden of varicella across the Middle East, gain insight into the evidence to support using universal varicella vaccination (UVV), and identify potential data gaps. Both epidemiology and economic data on the burden of varicella were limited and varied significantly. Most of the data focussed on varicella burden in the absence of a UVV program. In the absence of UVV, varicella incidence is increasing across this region with varicella infection associated with substantial morbidity. Although limited, data on the impact of vaccination at a population level indicated UVV programs reduce varicella incidence and hospitalizations, in line with global experience. Further research and action are needed to better understand varicella epidemiology in the Middle East, increase awareness and understanding in the region, and provide local data to support national public-health decisions regarding the implementation of UVV programs.