Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial

ERDOĞAN KAYHAN G., ŞANLI M., Ozgul U., Kirteke R., YOLOĞLU S.

JOURNAL OF CLINICAL ANESTHESIA, vol.50, pp.5-11, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50
  • Publication Date: 2018
  • Doi Number: 10.1016/j.jclinane.2018.06.030
  • Journal Name: JOURNAL OF CLINICAL ANESTHESIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.5-11
  • Keywords: Ibuprofen intravenous solution, Acetaminophen, Bariatric surgery, Pain, postoperative, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, PLACEBO-CONTROLLED TRIAL, DOUBLE-BLIND, ANASTOMOTIC LEAKAGE, IV-IBUPROFEN, MULTICENTER, PARACETAMOL, REDUCTION, ANALGESIA, EFFICACY
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Study objective: Multimodal analgesic strategies are recommended to decrease opioid requirements and opioid-induced respiratory complications in patients undergoing laparoscopic bariatric surgery. Recent studies have demonstrated that intravenous ibuprofen decreases opioid consumption compared with placebo. The primary aim of this study was to compare the effect of intravenous ibuprofen and intravenous acetaminophen on opioid consumption. We also aimed to compare postoperative pain levels and side effects of the drugs.