The relationship of osteopontin and related cytokin levels with disease activity, treatment and comorbidities in psoriasis vulgaris

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Atıf İçin Kopyala

Bulur I., Gulekon A., Erdem O., Yucel A. A., Celik S., Aral A.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, cilt.47, sa.3, ss.142-147, 2013 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 47 Sayı: 3
• Basım Tarihi: 2013
• Doi Numarası: 10.4274/turkderm.55798
• Dergi Adı: TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.142-147
• Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background and Design: The IL23/Th17 axis is an exciting new pathway in the pathogenesis of psoriasis. Osteopontin (OPN) is a recently defined phosphorylated acidic glycoprotein which has an effect on psoriasis, especially over Th1/Th17 cells. We aimed to understand the role of OPN and Th1/Th17 pathway in the immunopathogenesis of psoriasis, to assess its relationship with disease severity and to introduce the potential target molecules for therapeutic intervention in psoriatic patients. Materials and