Akademik Veri Yönetim Sistemi
9th International Conference of Nutrition and Growth, 17 - 19 Mart 2022, ss.252
Background and Aims:
IInfantile colic (IC) is a common problem during infancy. The exact pathophysiology is still unknown. In this study, we evaluated the presence of previously identified risk factors for dysbiosis in children with IC and presumed healthy children.
Methods:
We performed a cross-sectional electronic survey contained questions about microbiota related factors, with a national convenience sample of 427 children with IC and 2165 presumed healthy children, in Turkey.
Results:
Infant sex, parental age, maternal weight at conception and at delivery, weight gain during pregnancy, birth weight, prevalence of prematurity, number of siblings, number of family members at home, type of residency and presence of garden are similar in the IC group and controls. C-section was significantly higher in IC group(p<0.05) and emergency C-section was significantly higher in the IC group(p<0.001). Antibiotic use during delivery or during the first 7 days of life were significantly higher in IC group(p<0.001). There was no difference in breastfeeding at day 1 of life and also the prevalence of exclusive breastfeeding during the first six months between both groups(p>0.05). were as well similar. 134 (31.1%) infants received probiotics (74.6% Lactobacillus reuterii DSM17938) for IC. The presumed diagnoses of cow's milk allergy (CMA) are higher in IC group(p<0.001).
Conclusions:
The prevalence C-section, mainly emergency C-section, and antibiotic use during delivery or during the first 7 days of life are more frequent in IC group. Other microbiota related risk factors during first 1000 days of life were similar between children with or without IC. CMA is common in children with IC.