NORTHERN CLINICS OF ISTANBUL, vol.5, no.4, pp.277-281, 2018 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
NORTHERN CLINICS OF ISTANBUL
Bone, cancer, granulocyte colony-stimulating factor, hematopoietic growth factor, PERIPHERAL-BLOOD STEM, BIOCHEMICAL MARKERS, OSTEOPOROSIS, OVEREXPRESSION, NEUTROPENIA, INHIBITION, GROWTH, CSF
OBJECTIVE: The granulocyte colony-stimulating factor (G-CSF) is the most commonly used hematopoietic growth factor recombinant DNA technology. It affects bone metabolism by modulating both osteoclast and osteoblast functions. The aim of the present study was to investigate the effects of short-term use of G-CSF on bone metabolism in children with leukemia and solid tumors.