Study on the Antimicrobial Effects of Novel Thiazole Derivatives


CANKILIÇ M. Y. , YURTTAŞ L.

MARMARA PHARMACEUTICAL JOURNAL, vol.21, no.3, pp.654-659, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.12991/marupj.323584
  • Journal Name: MARMARA PHARMACEUTICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.654-659
  • Eskisehir Osmangazi University Affiliated: No

Abstract

In this work, six 2-[(1/4-methylimidazol/triazol/tetrazol-2/3/5-yl) thio]-N-(4-substituted thiazol-2-yl) acetamide derivatives (2a-f) were synthesized. The antimicrobial activities of these substances were examined against some foodborne Gram positive and Gram negative test bacteria, Candida albicans, Candida glabrata, Candida krusei, and Candida parapsilosis yeasts, and some Aspergillus and Penicillium filamentous fungi species. The substances were shown considerable antimicrobial effect to tested pathogenic microorganisms.