Silicon-based one-dimensional photonic crystal biosensor for the detection of prostate-specific antigen (PSA)
Phosphorus, Sulfur and Silicon and the Related Elements, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 2026
- Doi Numarası: 10.1080/10426507.2026.2734157
- Dergi Adı: Phosphorus, Sulfur and Silicon and the Related Elements
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Academic Search Ultimate (EBSCO), Materials Science & Engineering Collection (ProQuest), Technology Collection (ProQuest)
- Anahtar Kelimeler: defect modes, impedance approach, Photonic crystal, prostate-specific antigen (PSA), sensor
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
In this study, a one-dimensional photonic crystal (1D PC)-based refractive index biosensor for detecting prostate-specific antigen (PSA) is theoretically analyzed. A defective Si/SiO2 photonic crystal structure is proposed. The defect layer consists of healthy and prostate cancer blood samples to detect prostate-specific antigen (PSA). The variation in the refractive index (RI) of the analyte induces a shift in the defect mode resonance within the photonic band gap, forming the fundamental sensing mechanism of the proposed biosensor. The impedance approach was used to analyze the transmission spectrum. A high sensitivity of 3214.5 nm/RIU was achieved for the proposed biosensor. This structure has the potential for highly sensitive detection and sensing of PSA in human blood samples.