Lake Acigol of Turkey is a perennial lake with a brine composition of Na-Cl-SO4. The lake is fed mainly by two distinct water sources. The first is groundwater of Mg-HCO, type and springs of Na-SO, type. The difference in composition of inflow waters is attributed to different ways of water cycling. Ephemeral mudflats around Lake Acigol are composed of gypsum, calcite, dolomite, huntite, together with elastic minerals. Brine-soaked mudflat exist locally and contain efflorescence of halite, bloedite; thenardite and/or mirabilite precipitating from the artesian groundwater; Dominance of aragonite and high TOC values recorded in the gel-like lake sediments are the indicator of bacterial activity in the lake. Fluid-mineral equilibria calculations performed on the waters of the Lake Acigol basin successfully predicted precipitation of minerals detected in the recent sediments.