A facile synthesis of some thieno/furo-[2,3-d]pyrimidine-2-yl-thioacetic acid derivatives


Demirayak S., Abu Mohsen U.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.38, no.2, pp.507-509, 2001 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2001
  • Doi Number: 10.1002/jhet.5570380234
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.507-509

Abstract

The reaction of 2-(alpha -chloroacetamido)-3-cyano-4, 5-disubstituted thiophenes/furanes with ammonium thiocyanate in methanol or ethanol afforded methyl or ethyl (4-amino-5,6-disubstituted thieno/furo[2,3-d]pyrimidine-2-yl)thioacetates in good yields.