Recent developments in cancer therapy have resulted in increases in treatment success rates and survival. One of the basic goals of such therapy is improving patient quality of life. Chemotherapy protocols for solid or hematological malignancies-most of which include multiple agents-negatively impact patient quality of life. Additionally, there have been developments in supportive care, which seeks to ameliorate or minimize the negative effects of chemotherapy. Herein we present a review and brief summarization of some of the agents used for supportive care in cancer patients in light of the latest guidelines..