HLA-DQ2/DQ8 frequency in adult patients with celiac disease, their first-degree relatives, and normal population in Turkey


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Ozgenel S. M., TEMEL T., ÜSKÜDAR TEKE H., YILDIZ P., KORKMAZ H., ÖZAKYOL A.

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.30, no.4, pp.321-325, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.5152/tjg.2019.18255
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.321-325
  • Keywords: Celiac disease, HLA DQ2, HLA DQ8, Turkish population, TURKISH CHILDREN, HLA, PREVALENCE, DIAGNOSIS, SEVERITY, ALLELES
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background/Aims: Celiac disease is an autoimmune, familial disease that results in susceptibility to gluten in cereal and cereal products in genetically susceptible individuals. The aim of the present study was to investigate the presence of HLA-DQ2/DQ8 in patients with celiac disease, their first-degree relatives, and healthy community.