Toplum kökenli ürosepsis: Risk faktörleri, klinik ve etiyolojik deǧerlendirme


Naz H., Aykin N., Çevik F. Ç., ÖZAKIN E.

Turkiye Klinikleri Journal of Medical Sciences, cilt.29, sa.4, ss.866-871, 2009 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2009
  • Dergi Adı: Turkiye Klinikleri Journal of Medical Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.866-871
  • Anahtar Kelimeler: Sepsis, Urinary tract infections
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to investigate the risk factors, clinical, etiologic, laboratory and treatment data of urosepsis (US) cases, among those monitored for community acquired urinary system infections (CAUSI). Material and Methods: The patients monitored in our CAUSI between January 2005 and January 2008, were analyzed retrospectively. Results: During the study period, 229 CAUSI and 71 (31%) US cases were determined. Among the 229 cases diagnosed as CAUSI, 306 risk factors were determined in 149 patients. While 90% (64/71) of cases with US had risk factors, only 54% (85/158) of those without US (p= 0.000). Among all risk factors for US cases within the CAUSI group, age (p= 0.004), diabetes mellitus (DM) (p= 0.000), neurological disease (p= 0.002), chronic obstructive pulmonary disease (COPD) (p= 0.012) and immunosuppressive host (p= 0.038) were significantly higher in comparison to cases without US. The most common agents in cases with and without US were Escherichia coli, Klebsiella spp. and Enterococci sp. Conclusion: CAUSI cases with older age, DM, neurological disease, COPD, and immunosupression are under risk for the development of US. The agents responsible for CAUSI, though they have different ratios, are not different from those isolated in cases without US. Because of the high mortality rates, treatment with wide spectrum antibiotics, supportive treatment and appropriate medical and surgical therapy aiming any underlying disease would be appropriate in cases with US. Copyright © 2009 by Türkiye Klinikleri.