Low dose chemotherapeutic drugs without overt cytotoxic effects decrease the secretion of VEGF by cultured human tumor cells: A tentative relationship between drug type and tumor cell type response

Aktas S. H. , Akbulut H., Akgun N., Icli F.

CANCER BIOMARKERS, cilt.12, sa.3, ss.135-140, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Konu: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3233/cbm-130301
  • Sayfa Sayıları: ss.135-140


BACKGROUND: The metronomic use of chemotherapeutic drugs is presumed to have anti-angiogenic effect. In the current study, we aimed to test the effects of lower doses of cytotoxic agents on VEGF secretion from tumor cell lines.