THROMBOELASTOGRAPHIC EVALUATION OF COAGULATION IN A SEPTIC CALF


Eralp İnan O.

9 INTERNATIONAL BLACK SEA COASTLINE COUNTRIESSCIENTIFIC RESEARCH CON, Ankara, Türkiye, 10 - 11 Ağustos 2023, ss.303, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Ankara
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.303
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Thromboealstography (TEG) is a widely used method for the evaluation of hemostasis in human and veterinary medicine. One of the important features of TEG is the fact it can detect hypo- and hypercoagulable states as well as hypo- and hyperfibrinolytic states. TEG is well studied in hypercoagulable states related to compensated disseminated intravascular coagulation (DIC). Diseases resulting in endotoxemia and sepsis in ruminants are known to be cause of DIC. The aim was to establish coagulation abnormalities in a septic calve compared to a healthy one via TEG analysis. 

TEG evaluation was performed in one healthy and one septic Holstein male calves, 3 months of age. Included TEG measurements were R and K time, angle , MA and G. TEG measurement results in the healthy calve were R: 6.8 min., K: 3 min., angle : 48°, MA: 69.1 mm and G: 21dyn/sec. TEG measurement results in the septic calve were R: 6.3 min., K: 1.4min., angle : 68.5°, MA: 77.8mm and G: 17.5dyn/sec. 

Based on the TEG variables R, K and MA evaluations, the septic calf had shown a hypercoagulable state. The G value was surprisingly higher in the healthy calve. DIC can be detected in a hypercoagulative state as well as in a hypocoagulative state. TEG use in claves for the assessment of coagulation could be clinically relevant. Further investigations, like reference intervals and analysis in diseased calves should be performed for a better interpretation of results.