Protective Effects of Zinc on Testes of Cadmium-Treated Rats


BURUKOĞLU DÖNMEZ D., Baycu C.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, vol.81, no.6, pp.521-524, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 81 Issue: 6
  • Publication Date: 2008
  • Doi Number: 10.1007/s00128-007-9211-x
  • Journal Name: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.521-524
  • Keywords: Cadmium, testicular damage, Zinc, Rat, METALLOTHIONEIN, TOXICITY, LEAD
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

In this microscopic study, the toxic effects of cadmium (Cd) and the protective role of a zinc (Zn) co-treatment were investigated in the testes of the rats treated with Cd. At the dose and duration used, Cd severely damaged the seminiferous tubules and caused the degeneration and disintegration of spermatogenic cells. Leydig cells were also lost after Cd treatment. The present study showed that zinc co-treatment protected testes against toxic effects of cadmium.