Effect of benzothiazole/piperazine derivatives on intracerebroventricular streptozotocin-induced cognitive deficits


Oezkay U. D. , CAN Ö. D. , ÖZKAY Y., ÖZTÜRK Y.

PHARMACOLOGICAL REPORTS, vol.64, no.4, pp.834-847, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.1016/s1734-1140(12)70878-2
  • Title of Journal : PHARMACOLOGICAL REPORTS
  • Page Numbers: pp.834-847

Abstract

Background: In this study, benzothiazolc-piperazine compounds were synthesized by condensing the functional groups of donepezil (DNP), FK-960, and sabeluzole, which are known to have therapeutic potential against Alzheimer's disease, with the aim of obtaining new and potent anti-Alzheimer agents.